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  • 2024 Vol. 41, No. 3
    《Journal of clinical internal medicine》
    主管单位:湖北省卫生和计划生育委员会
    主办单位:中华医学会湖北分会
    地  址:武汉市武昌区东湖路165号
    电  话:027-87893477
    电子邮件:lcnkzz@sina.com
    国际标准刊号:ISSN 1001-9057
    国内统一刊号:CN 42-1139/R
    邮发代号:430071
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Effect of hemodialysis and peritoneal dialysis on microinflammation of uremia patients in chronic renal failure and its relationship with cardiovascular disease
Journal of clinical internal medicine    2019, 36 (11): 748-750.   DOI: 10.3969/j.issn.1001-9057.2019.11.010
Abstract310)      PDF (299KB)(4597)   

Objective To explore the effects of hemodialysis and peritoneal dialysis on microinflammation of chronic renal failure(CRF)uremic patients and its relationship with cardiovascular disease.Methods A total of 120 CRF uremic patients treated in our hospital were divided into hemodialysis group(60 cases) and peritonealdialysis group(60 cases) according to the type of dialysis.After 6 months of treatment,the levels of C reactive protein(CRP),tumor necrosis factor(TNF)-α,interleukin(IL)-1β,IL-6 btween the two groups were compared.Patients in the two groups were divided into the group with and without chronic heart failure(CHF) according to the presence or absence of combined with CHF,the levels of TNF-α、IL-1β,IL-6 in each group were compared.Results There were no significant differences in the levels of CRP,TNF-α,IL-1β,IL-6 between the two groups before treatment(P>0.05).After treatment,the levels of TNF-α,IL-1β,IL-6 in both groups were significantly reduced than the same group before treatment(P<0.05),the levels of TNF-α,IL-1β,IL-6 in the peritoneal dialysis group were lower than those in the hemodialysis group(P<0.05).In patients with CHF,the levels of TNF-α,IL-1β,IL-6 in patients of the group with heart failure were significantly higher than those in the same group of the group without heart failure(P<0.05).Conclusion Both hemodialysis and peritoneal dialysis can reduce the level of TNF-α,IL-1β,IL-6 in CRF uremic patients,and peritoneal dialysis is better.Microinflammation is correlated with cardiovascular disease.

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Journal of clinical internal medicine    2019, 36 (10): 649-652.   DOI: 10.3969/j.issn.1001-9057.2019.10.001
Abstract396)      PDF (364KB)(4090)   
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Journal of clinical internal medicine    2020, 37 (4): 247-249.   DOI: 10.3969/j.issn.1001-9057.2020.04.001
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Journal of clinical internal medicine    2020, 37 (6): 460-462.   DOI: 10.3969/j.issn.1001-9057.2020.06.022
Abstract1239)   HTML113)    PDF (358KB)(3392)   
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Journal of clinical internal medicine    2020, 37 (7): 528-531.   DOI: 10.3969/j.issn.1001-9057.2020.07.022
Abstract1000)   HTML89)    PDF (402KB)(3073)   
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Journal of clinical internal medicine    2019, 36 (10): 662-664.   DOI: 10.3969/j.issn.1001-9057.2019.10.005
Abstract338)      PDF (325KB)(2854)   
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Journal of clinical internal medicine    2020, 37 (10): 689-692.   DOI: 10.3969/j.issn.1001-9057.2020.10.004
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Journal of clinical internal medicine    2021, 38 (2): 87-89.   DOI: 10.3969/j.issn.1001-9057.2021.02.005
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Journal of clinical internal medicine    2020, 37 (4): 281-286.   DOI: 10.3969/j.issn.1001-9057.2020.04.012
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Journal of clinical internal medicine    2020, 37 (10): 679-680.   DOI: 10.3969/j.issn.1001-9057.2020.10.001
Abstract263)   HTML33)    PDF (298KB)(1632)   
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Journal of clinical internal medicine    2020, 37 (9): 607-610.   DOI: 10.3969/j.issn.1001-9057.2020.09.001
Abstract288)   HTML33)    PDF (377KB)(1577)   
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Journal of clinical internal medicine    2020, 37 (4): 253-255.   DOI: 10.3969/j.issn.1001-9057.2020.04.003
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Journal of clinical internal medicine    2019, 36 (10): 652-655.   DOI: 10.3969/j.issn.1001-9057.2019.10.002
Abstract296)      PDF (365KB)(1395)   
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Journal of clinical internal medicine    2019, 36 (10): 665-667.   DOI: 10.3969/j.issn.1001-9057.2019.10.006
Abstract244)      PDF (315KB)(1392)   
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Journal of clinical internal medicine    2021, 38 (2): 90-93.   DOI: 10.3969/j.issn.1001-9057.2021.02.006
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Journal of clinical internal medicine    2019, 36 (10): 659-661.   DOI: 10.3969/j.issn.10019057.2019.10.004
Abstract305)      PDF (311KB)(1349)   
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Journal of clinical internal medicine    2019, 36 (12): 793-795.   DOI: 10.3969/j.issn.1001-9057.2019.12.001
Abstract261)      PDF (313KB)(1343)   
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Journal of clinical internal medicine    2020, 37 (6): 409-413.   DOI: 10.3969/j.issn.1001-9057.2020.06.006
Abstract175)   HTML29)    PDF (390KB)(1319)   
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Journal of clinical internal medicine    2020, 37 (6): 394-396.   DOI: 10.3969/j.issn.1001-9057.2020.06.002
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Journal of clinical internal medicine    2021, 38 (10): 710-712.   DOI: 10.3969/j.issn.1001-9057.2021.10.021
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Journal of clinical internal medicine    2020, 37 (5): 319-322.   DOI: 10.3969/j.issn.1001-9057.2020.05.001
Abstract253)   HTML70)    PDF (581KB)(1191)   
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Journal of clinical internal medicine    2020, 37 (4): 250-252.   DOI: 10.3969/j.issn.1001-9057.2020.04.002
Abstract228)   HTML34)    PDF (322KB)(1184)   
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Journal of clinical internal medicine    2020, 37 (5): 323-327.   DOI: 10.3969/j.issn.1001-9057.2020.05.002
Abstract216)   HTML60)    PDF (452KB)(1143)   
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Journal of clinical internal medicine    2020, 37 (9): 611-615.   DOI: 10.3969/j.issn.1001-9057.2020.09.002
Abstract157)   HTML15)    PDF (556KB)(1127)   
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Journal of clinical internal medicine    2020, 37 (9): 675-678.   DOI: 10.3969/j.issn.1001-9057.2020.09.023
Abstract218)   HTML39)    PDF (366KB)(1098)   
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Journal of clinical internal medicine    2019, 36 (12): 862-864.   DOI: 10.3969/j.issn.1001-9057.2019.12.024
Abstract192)      PDF (344KB)(1087)   
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Journal of clinical internal medicine    2020, 37 (3): 206-208.   DOI: 10.3969/j.issn.1001-9057.2020.03.021
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Journal of clinical internal medicine    2019, 36 (10): 656-659.   DOI: 10.3969/j.issn.1001-9057.2019.10.003
Abstract226)      PDF (351KB)(1037)   
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Journal of clinical internal medicine    2017, 34 (1): 5-.   DOI: 10.3969/j.issn.1001-9057.2017.01.001
Abstract147)      PDF (1469KB)(1029)   
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Journal of clinical internal medicine    2020, 37 (10): 684-688.   DOI: 10.3969/j.issn.1001-9057.2020.10.003
Abstract195)   HTML15)    PDF (505KB)(1025)   
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Journal of clinical internal medicine    2019, 36 (12): 799-803.   DOI: 10.3969/j.issn.1001-9057.2019.12.003
Abstract247)      PDF (376KB)(981)   
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Journal of clinical internal medicine    2019, 36 (11): 727-729.  
Abstract237)      PDF (317KB)(960)   
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Journal of clinical internal medicine    2020, 37 (4): 264-267.   DOI: 10.3969/j.issn.1001-9057.2020.04.006
Abstract231)   HTML36)    PDF (329KB)(942)   
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Changes of thyroid function of type 2 diabetic patients with different body mass index and waist circumference
Journal of clinical internal medicine    2019, 36 (11): 755-758.   DOI: 10.3969/j.issn.1001-9057.2019.11.012
Abstract276)      PDF (374KB)(915)   
Objective To explore the changes of thyroid stimulating hormone(TSH) and thyroid hormone(TH) levels in type 2 diabetic patients with different body mass index(BMI) and waist circumference(WC) and the influence of obesity on TSH and TH.Methods A total of 275 hospitalized patients with type 2 diabetes were collected.They were divided into the normal group(18.5kg/m2≤BMI<24kg/m2,88 cases),overweight group(24kg/m2≤BMI<28kg/m2,90 cases) and obesity group(BMI≥28kg/m2,97cases) according to BMI.The blood lipid levels and thyroid function among these three groups were compared.Then,them were divided into M1 group(male WC<85cm),M2 group(male WC≥85cm),F1 group(female WC<80cm),F2 group(female WC≥80cm) according to gender and WC.Make a comparison among the above indexes among these groups.Spearman correlation analysis was used to analyze correlation and multiple linear stepwise regression was used for influence factor analysis.Results Compared with the normal group,TSH levels in the overweight group and obesity group were significantly increased(P<0.05).TSH level in F2 group was obviously higher than those in F1 group and M2 group,and free thyroxine(FT4) level was lower than that in M2 group(P<0.05).The results of correlation analysis showed that BMI of type 2 diabetic patients was positively correlated with TSH(r=0.25,P<0.05),TC was negatively related with FT3(r=-0.39,P<0.05),and BMI and WC were negatively related with FT4(r=-0.31,r=-0.29,P<0.05).The results of multiple linear stepwise regression showed that BMI was an independent correlative factor for TSH,and WC was an independent correlative factor for FT4(P<0.05).Conclusion The TSH level of obese patients with type 2 diabetes is increased,and FT4 is decreased,which are more obvious in female patients with abdominal obesity than those in males.
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Journal of clinical internal medicine    2020, 37 (7): 463-466.   DOI: 10.3969/j.issn.1001-9057.2020.07.001
Abstract194)   HTML30)    PDF (356KB)(907)   
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Journal of clinical internal medicine    2020, 37 (10): 681-683.   DOI: 10.3969/j.issn.1001-9057.2020.10.002
Abstract160)   HTML21)    PDF (331KB)(905)   
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Journal of clinical internal medicine    2019, 36 (11): 785-786.   DOI: 10.3969/j.issn.1001-9057.2019.11.023
Abstract335)      PDF (485KB)(898)   
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Efficacy and safety of radiofrequency catheter ablation for ventricular arrhythmias originated from the right ventricular outflow tract
Journal of clinical internal medicine    2019, 36 (12): 810-813.   DOI: 10.3969/j.issn.1001-9057.2019.12.006
Abstract367)      PDF (388KB)(887)   
Objective To explore the efficacy and safety of radiofrequency catheter ablation for ventricular arrhythmias originated from the right ventricular outflow tract(RVOT-VAs)and its influencing factors.Methods According to the success of a single operation or not,256 patients with RVOT-VAs undergoing radiofrequency catheter ablation were divided into successful single operation group(196 cases)and unsuccessful single operation group(60 cases),then general data and operational data of them were compared.Binary logistic regression analysis was performed to evaluate factors that affect the efficacy and safety of operation.Results In 256 patients,immediate success rate,single operation success rate and recurrence rate were 88.3%,76.6% and 13.2% respectively.Proportion of patients combined with hypertension and organic heart disease,QRS waves with various forms,surgical complications and pericardial tamponade in successful single operation group were lower than those in unsuccessful single operation group(P<0.05).Results of binary logistic regression analysis showed that combining organic heart disease,lack of experience for operators and target site of catheter ablation locating in free wall were independent risk factors for failure of single operation(P<0.05).Persistent ventricular tachycardial and target site of catheter ablation locating in free wall were independent risk factors for immediate failure of the first operation(P<0.05).Combining organic heart disease,lack of experience for operators,target site of catheter ablation locating in free wall and QRS waves with various forms were independent risk factors for recurrence after the first operation(P<0.05).Advanced age and lack of experience for operators were independent risk factors for complications during the first operation(P<0.05).Conclusion There is high success rate and safety of radiofrequency catheter ablation treating RVOT-VAs.Combining organic heart disease,target site of catheter ablation locating in free wall and the operator’s experience are important factors which affect the efficacy and safety.
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Journal of clinical internal medicine    2019, 36 (11): 770-772.   DOI: 10.3969/j.issn.1001-9057.2019.11.017
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Journal of clinical internal medicine    2020, 37 (3): 196-197.   DOI: 10.3969/j.issn.1001-9057.2020.03.017
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Journal of clinical internal medicine    2023, 40 (7): 497-499.   DOI: 10.3969/j.issn.1001-9057.2023.07.020
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Journal of clinical internal medicine    2023, 40 (10): 697-699.   DOI: 10.3969/j.issn.1001-9057.2023.10.013
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Journal of clinical internal medicine    2023, 40 (7): 462-465.   DOI: 10.3969/j.issn.1001-9057.2023.07.009
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Journal of clinical internal medicine    2023, 40 (7): 0-.  
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Journal of clinical internal medicine    2023, 40 (7): 433-437.   DOI: 10.3969/j.issn.1001-9057.2023.07.001
Abstract81)   HTML6)    PDF (727KB)(213)   
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Journal of clinical internal medicine    2023, 40 (10): 665-668.   DOI: 10.3969/j.issn.1001-9057.2023.10.004
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Journal of clinical internal medicine    2023, 40 (7): 460-461.   DOI: 10.3969/j.issn.1001-9057.2023.07.008
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Journal of clinical internal medicine    2023, 40 (7): 445-448.   DOI: 10.3969/j.issn.1001-9057.2023.07.004
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Journal of clinical internal medicine    2023, 40 (7): 449-452.   DOI: 10.3969/j.issn.1001-9057.2023.07.005
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Journal of clinical internal medicine    2023, 40 (5): 0-.  
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Journal of clinical internal medicine    2024, 41 (1): 42-46.   DOI: 10.3969/j.issn.1001-9057.2024.01.011
Abstract76)      PDF (399KB)(64)   
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Journal of clinical internal medicine    2023, 40 (12): 793-797.   DOI: 10.3969/j.issn.1001-9057.2023.12.001
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Journal of clinical internal medicine    2023, 40 (7): 478-481.   DOI: 10.3969/j.issn.1001-9057.2023.07.013
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Journal of clinical internal medicine    2023, 40 (7): 441-444.   DOI: 10.3969/j.issn.1001-9057.2023.07.003
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Journal of clinical internal medicine    2023, 40 (7): 495-496.   DOI: 10.3969/j.issn.1001-9057.2023.07.019
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Journal of clinical internal medicine    2023, 40 (10): 685-686.   DOI: 10.3969/j.issn.1001-9057.2023.10.009
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Journal of clinical internal medicine    2024, 41 (3): 208-209.   DOI: 10.3969/j.issn.1001-9057.2024.03.018
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Journal of clinical internal medicine    2023, 40 (7): 437-440.   DOI: 10.3969/j.issn.1001-9057.2023.07.002
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Journal of clinical internal medicine    2023, 40 (7): 466-470.   DOI: 10.3969/j.issn.1001-9057.2023.07.010
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Journal of clinical internal medicine    2023, 40 (8): 517-519.   DOI: 10.3969/j.issn.1001-9057.2023.08.004
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Journal of clinical internal medicine    2023, 40 (7): 493-495.   DOI: 10.3969/j.issn.1001-9057.2023.07.018
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Journal of clinical internal medicine    2023, 40 (7): 453-456.   DOI: 10.3969/j.issn.1001-9057.2023.07.006
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Journal of clinical internal medicine    2023, 40 (7): 457-460.   DOI: 10.3969/j.issn.1001-9057.2023.07.007
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Journal of clinical internal medicine    2023, 40 (7): 475-477.   DOI: 10.3969/j.issn.1001-9057.2023.07.012
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Journal of clinical internal medicine    2023, 40 (7): 502-504.   DOI: 10.3969/j.issn.1001-9057.2023.07.022
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Journal of clinical internal medicine    2023, 40 (7): 471-474.   DOI: 10.3969/j.issn.1001-9057.2023.07.011
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Journal of clinical internal medicine    2023, 40 (10): 681-685.   DOI: 10.3969/j.issn.1001-9057.2023.10.008
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Journal of clinical internal medicine    2023, 40 (12): 798-801.   DOI: 10.3969/j.issn.1001-9057.2023.12.002
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Journal of clinical internal medicine    2023, 40 (11): 0-.  
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Journal of clinical internal medicine    2023, 40 (7): 491-492.   DOI: 10.3969/j.issn.1001-9057.2023.07.017
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Journal of clinical internal medicine    2023, 40 (10): 672-676.   DOI: 10.3969/j.issn.1001-9057.2023.10.006
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Journal of clinical internal medicine    2023, 40 (8): 505-508.   DOI: 10.3969/j.issn.1001-9057.2023.08.001
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Journal of clinical internal medicine    2023, 40 (10): 0-.  
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Journal of clinical internal medicine    2023, 40 (12): 811-814.   DOI: 10.3969/j.issn.1001-9057.2023.12.005
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Journal of clinical internal medicine    2024, 41 (1): 1-4.   DOI: 10.3969/j.issn.1001-9057.2024.01.001
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Journal of clinical internal medicine    2023, 40 (8): 563-564.   DOI: 10.3969/j.issn.1001-9057.2023.08.018
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Journal of clinical internal medicine    2023, 40 (7): 482-486.   DOI: 10.3969/j.issn.1001-9057.2023.07.014
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Journal of clinical internal medicine    2023, 40 (10): 649-653.   DOI: 10.3969/j.issn.1001-9057.2023.10.001
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Journal of clinical internal medicine    2024, 41 (2): 0-.  
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Journal of clinical internal medicine    2023, 40 (7): 486-488.   DOI: 10.3969/j.issn.1001-9057.2023.07.015
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