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  • 2024 Vol. 41, No. 7
    《Journal of clinical internal medicine》
    主管单位:湖北省卫生和计划生育委员会
    主办单位:中华医学会湖北分会
    地  址:武汉市武昌区东湖路165号
    电  话:027-87893477
    电子邮件:lcnkzz@sina.com
    国际标准刊号:ISSN 1001-9057
    国内统一刊号:CN 42-1139/R
    邮发代号:430071
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Journal of clinical internal medicine    2019, 36 (10): 649-652.   DOI: 10.3969/j.issn.1001-9057.2019.10.001
Abstract418)      PDF (364KB)(5553)   
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Journal of clinical internal medicine    2020, 37 (4): 247-249.   DOI: 10.3969/j.issn.1001-9057.2020.04.001
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Effect of hemodialysis and peritoneal dialysis on microinflammation of uremia patients in chronic renal failure and its relationship with cardiovascular disease
Journal of clinical internal medicine    2019, 36 (11): 748-750.   DOI: 10.3969/j.issn.1001-9057.2019.11.010
Abstract323)      PDF (299KB)(4661)   

Objective To explore the effects of hemodialysis and peritoneal dialysis on microinflammation of chronic renal failure(CRF)uremic patients and its relationship with cardiovascular disease.Methods A total of 120 CRF uremic patients treated in our hospital were divided into hemodialysis group(60 cases) and peritonealdialysis group(60 cases) according to the type of dialysis.After 6 months of treatment,the levels of C reactive protein(CRP),tumor necrosis factor(TNF)-α,interleukin(IL)-1β,IL-6 btween the two groups were compared.Patients in the two groups were divided into the group with and without chronic heart failure(CHF) according to the presence or absence of combined with CHF,the levels of TNF-α、IL-1β,IL-6 in each group were compared.Results There were no significant differences in the levels of CRP,TNF-α,IL-1β,IL-6 between the two groups before treatment(P>0.05).After treatment,the levels of TNF-α,IL-1β,IL-6 in both groups were significantly reduced than the same group before treatment(P<0.05),the levels of TNF-α,IL-1β,IL-6 in the peritoneal dialysis group were lower than those in the hemodialysis group(P<0.05).In patients with CHF,the levels of TNF-α,IL-1β,IL-6 in patients of the group with heart failure were significantly higher than those in the same group of the group without heart failure(P<0.05).Conclusion Both hemodialysis and peritoneal dialysis can reduce the level of TNF-α,IL-1β,IL-6 in CRF uremic patients,and peritoneal dialysis is better.Microinflammation is correlated with cardiovascular disease.

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Journal of clinical internal medicine    2020, 37 (6): 460-462.   DOI: 10.3969/j.issn.1001-9057.2020.06.022
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Journal of clinical internal medicine    2020, 37 (7): 528-531.   DOI: 10.3969/j.issn.1001-9057.2020.07.022
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Journal of clinical internal medicine    2019, 36 (10): 662-664.   DOI: 10.3969/j.issn.1001-9057.2019.10.005
Abstract360)      PDF (325KB)(3014)   
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Journal of clinical internal medicine    2021, 38 (2): 87-89.   DOI: 10.3969/j.issn.1001-9057.2021.02.005
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Journal of clinical internal medicine    2020, 37 (10): 689-692.   DOI: 10.3969/j.issn.1001-9057.2020.10.004
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Journal of clinical internal medicine    2020, 37 (4): 281-286.   DOI: 10.3969/j.issn.1001-9057.2020.04.012
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Journal of clinical internal medicine    2020, 37 (10): 679-680.   DOI: 10.3969/j.issn.1001-9057.2020.10.001
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Journal of clinical internal medicine    2020, 37 (9): 607-610.   DOI: 10.3969/j.issn.1001-9057.2020.09.001
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Journal of clinical internal medicine    2020, 37 (4): 253-255.   DOI: 10.3969/j.issn.1001-9057.2020.04.003
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Journal of clinical internal medicine    2019, 36 (10): 659-661.   DOI: 10.3969/j.issn.10019057.2019.10.004
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Journal of clinical internal medicine    2021, 38 (2): 90-93.   DOI: 10.3969/j.issn.1001-9057.2021.02.006
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Journal of clinical internal medicine    2019, 36 (10): 652-655.   DOI: 10.3969/j.issn.1001-9057.2019.10.002
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Journal of clinical internal medicine    2019, 36 (10): 665-667.   DOI: 10.3969/j.issn.1001-9057.2019.10.006
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Journal of clinical internal medicine    2020, 37 (6): 394-396.   DOI: 10.3969/j.issn.1001-9057.2020.06.002
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Journal of clinical internal medicine    2020, 37 (5): 319-322.   DOI: 10.3969/j.issn.1001-9057.2020.05.001
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Journal of clinical internal medicine    2020, 37 (6): 409-413.   DOI: 10.3969/j.issn.1001-9057.2020.06.006
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Journal of clinical internal medicine    2019, 36 (12): 793-795.   DOI: 10.3969/j.issn.1001-9057.2019.12.001
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Journal of clinical internal medicine    2017, 34 (1): 5-.   DOI: 10.3969/j.issn.1001-9057.2017.01.001
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Journal of clinical internal medicine    2020, 37 (4): 250-252.   DOI: 10.3969/j.issn.1001-9057.2020.04.002
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Journal of clinical internal medicine    2021, 38 (10): 710-712.   DOI: 10.3969/j.issn.1001-9057.2021.10.021
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Journal of clinical internal medicine    2020, 37 (9): 611-615.   DOI: 10.3969/j.issn.1001-9057.2020.09.002
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Journal of clinical internal medicine    2020, 37 (5): 323-327.   DOI: 10.3969/j.issn.1001-9057.2020.05.002
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Journal of clinical internal medicine    2020, 37 (9): 675-678.   DOI: 10.3969/j.issn.1001-9057.2020.09.023
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Journal of clinical internal medicine    2019, 36 (12): 862-864.   DOI: 10.3969/j.issn.1001-9057.2019.12.024
Abstract204)      PDF (344KB)(1212)   
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Journal of clinical internal medicine    2019, 36 (10): 656-659.   DOI: 10.3969/j.issn.1001-9057.2019.10.003
Abstract238)      PDF (351KB)(1171)   
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Journal of clinical internal medicine    2020, 37 (10): 684-688.   DOI: 10.3969/j.issn.1001-9057.2020.10.003
Abstract209)   HTML15)    PDF (505KB)(1166)   
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Journal of clinical internal medicine    2020, 37 (3): 206-208.   DOI: 10.3969/j.issn.1001-9057.2020.03.021
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Journal of clinical internal medicine    2019, 36 (12): 799-803.   DOI: 10.3969/j.issn.1001-9057.2019.12.003
Abstract269)      PDF (376KB)(1109)   
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Journal of clinical internal medicine    2020, 37 (9): 616-619.   DOI: 10.3969/j.issn.1001-9057.2020.09.003
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Journal of clinical internal medicine    2020, 37 (7): 463-466.   DOI: 10.3969/j.issn.1001-9057.2020.07.001
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Journal of clinical internal medicine    2020, 37 (10): 681-683.   DOI: 10.3969/j.issn.1001-9057.2020.10.002
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Journal of clinical internal medicine    2021, 38 (3): 155-158.   DOI: 10.3969/j.issn.1001-9057.2021.03.004
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Journal of clinical internal medicine    2020, 37 (3): 196-197.   DOI: 10.3969/j.issn.1001-9057.2020.03.017
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Journal of clinical internal medicine    2019, 36 (11): 727-729.  
Abstract248)      PDF (317KB)(1018)   
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Journal of clinical internal medicine    2020, 37 (4): 264-267.   DOI: 10.3969/j.issn.1001-9057.2020.04.006
Abstract249)   HTML36)    PDF (329KB)(987)   
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Journal of clinical internal medicine    2021, 38 (11): 727-730.   DOI: 10.3969/j.issn.1001-9057.2021.11.003
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Changes of thyroid function of type 2 diabetic patients with different body mass index and waist circumference
Journal of clinical internal medicine    2019, 36 (11): 755-758.   DOI: 10.3969/j.issn.1001-9057.2019.11.012
Abstract285)      PDF (374KB)(968)   
Objective To explore the changes of thyroid stimulating hormone(TSH) and thyroid hormone(TH) levels in type 2 diabetic patients with different body mass index(BMI) and waist circumference(WC) and the influence of obesity on TSH and TH.Methods A total of 275 hospitalized patients with type 2 diabetes were collected.They were divided into the normal group(18.5kg/m2≤BMI<24kg/m2,88 cases),overweight group(24kg/m2≤BMI<28kg/m2,90 cases) and obesity group(BMI≥28kg/m2,97cases) according to BMI.The blood lipid levels and thyroid function among these three groups were compared.Then,them were divided into M1 group(male WC<85cm),M2 group(male WC≥85cm),F1 group(female WC<80cm),F2 group(female WC≥80cm) according to gender and WC.Make a comparison among the above indexes among these groups.Spearman correlation analysis was used to analyze correlation and multiple linear stepwise regression was used for influence factor analysis.Results Compared with the normal group,TSH levels in the overweight group and obesity group were significantly increased(P<0.05).TSH level in F2 group was obviously higher than those in F1 group and M2 group,and free thyroxine(FT4) level was lower than that in M2 group(P<0.05).The results of correlation analysis showed that BMI of type 2 diabetic patients was positively correlated with TSH(r=0.25,P<0.05),TC was negatively related with FT3(r=-0.39,P<0.05),and BMI and WC were negatively related with FT4(r=-0.31,r=-0.29,P<0.05).The results of multiple linear stepwise regression showed that BMI was an independent correlative factor for TSH,and WC was an independent correlative factor for FT4(P<0.05).Conclusion The TSH level of obese patients with type 2 diabetes is increased,and FT4 is decreased,which are more obvious in female patients with abdominal obesity than those in males.
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Journal of clinical internal medicine    2024, 41 (3): 208-209.   DOI: 10.3969/j.issn.1001-9057.2024.03.018
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Journal of clinical internal medicine    2023, 40 (11): 0-.  
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Journal of clinical internal medicine    2023, 40 (10): 0-.  
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Journal of clinical internal medicine    2024, 41 (3): 165-169.   DOI: 10.3969/j.issn.1001-9057.2024.03.006
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Journal of clinical internal medicine    2023, 40 (12): 0-.  
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Journal of clinical internal medicine    2024, 41 (3): 202-203.   DOI: 10.3969/j.issn.1001-9057.2024.03.015
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Journal of clinical internal medicine    2024, 41 (3): 210-212.   DOI: 10.3969/j.issn.1001-9057.2024.03.019
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Journal of clinical internal medicine    2024, 41 (3): 191-193.   DOI: 10.3969/j.issn.1001-9057.2024.03.012
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Journal of clinical internal medicine    2024, 41 (4): 0-0.  
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Journal of clinical internal medicine    2024, 41 (3): 149-151.   DOI: 10.3969/j.issn.1001-9057.2024.03.002
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Journal of clinical internal medicine    2024, 41 (3): 160-164.   DOI: 10.3969/j.issn.1001-9057.2024.03.005
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Journal of clinical internal medicine    2023, 40 (9): 0-.  
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Journal of clinical internal medicine    2024, 41 (3): 145-148.   DOI: 10.3969/j.issn.1001-9057.2024.03.001
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Journal of clinical internal medicine    2024, 41 (3): 152-155.   DOI: 10.3969/j.issn.1001-9057.2024.03.003
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Journal of clinical internal medicine    2024, 41 (3): 170-174.   DOI: 10.3969/j.issn.1001-9057.2024.03.007
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Journal of clinical internal medicine    2024, 41 (3): 183-186.   DOI: 10.3969/j.issn.1001-9057.2024.03.010
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Journal of clinical internal medicine    2024, 41 (5): 0-.  
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Journal of clinical internal medicine    2024, 41 (3): 187-190.   DOI: 10.3969/j.issn.1001-9057.2024.03.011
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Journal of clinical internal medicine    2024, 41 (3): 194-196.   DOI: 10.3969/j.issn.1001-9057.2024.03.013
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Journal of clinical internal medicine    2024, 41 (3): 179-183.   DOI: 10.3969/j.issn.1001-9057.2024.03.009
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Journal of clinical internal medicine    2024, 41 (3): 155-159.   DOI: 10.3969/j.issn.1001-9057.2024.03.004
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Journal of clinical internal medicine    2024, 41 (3): 175-178.   DOI: 10.3969/j.issn.1001-9057.2024.03.008
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Journal of clinical internal medicine    2024, 41 (1): 0-.  
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Journal of clinical internal medicine    2024, 41 (3): 206-208.   DOI: 10.3969/j.issn.1001-9057.2024.03.017
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Journal of clinical internal medicine    2024, 41 (3): 204-205.   DOI: 10.3969/j.issn.1001-9057.2024.03.016
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Journal of clinical internal medicine    2024, 41 (3): 197-202.   DOI: 10.3969/j.issn.1001-9057.2024.03.014
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Journal of clinical internal medicine    2024, 41 (3): 213-215.   DOI: 10.3969/j.issn.1001-9057.2024.03.020
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Journal of clinical internal medicine    2024, 41 (6): 0-.  
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Journal of clinical internal medicine    2024, 41 (3): 215-217.   DOI: 10.3969/j.issn.1001-9057.2024.03.021
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Journal of clinical internal medicine    2024, 41 (3): 218-220.   DOI: 10.3969/j.issn.1001-9057.2024.03.022
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Journal of clinical internal medicine    0, (): 0-.  
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Journal of clinical internal medicine    2024, 41 (7): 490-492.   DOI: 10.3969/j.issn.1001-9057.2024.07.014
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Journal of clinical internal medicine    2024, 41 (7): 503-504.   DOI: 10.3969/j.issn.1001-9057.2024.07.020
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Journal of clinical internal medicine    2024, 41 (7): 483-485.   DOI: 10.3969/j.issn.1001-9057.2024.07.012
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Journal of clinical internal medicine    2024, 41 (7): 446-450.   DOI: 10.3969/j.issn.1001-9057.2024.07.003
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Journal of clinical internal medicine    2024, 41 (7): 451-455.   DOI: 10.3969/j.issn.1001-9057.2024.07.004
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Journal of clinical internal medicine    2024, 41 (7): 0-.  
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