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  • 2025 Vol. 42, No. 3
    《Journal of clinical internal medicine》
    主管单位:湖北省卫生和计划生育委员会
    主办单位:中华医学会湖北分会
    地  址:武汉市武昌区东湖路165号
    电  话:027-87893477
    电子邮件:lcnkzz@sina.com
    国际标准刊号:ISSN 1001-9057
    国内统一刊号:CN 42-1139/R
    邮发代号:430071
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Journal of clinical internal medicine    2020, 37 (4): 247-249.   DOI: 10.3969/j.issn.1001-9057.2020.04.001
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Journal of clinical internal medicine    2019, 36 (10): 649-652.   DOI: 10.3969/j.issn.1001-9057.2019.10.001
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Journal of clinical internal medicine    2020, 37 (6): 460-462.   DOI: 10.3969/j.issn.1001-9057.2020.06.022
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Effect of hemodialysis and peritoneal dialysis on microinflammation of uremia patients in chronic renal failure and its relationship with cardiovascular disease
Journal of clinical internal medicine    2019, 36 (11): 748-750.   DOI: 10.3969/j.issn.1001-9057.2019.11.010
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Objective To explore the effects of hemodialysis and peritoneal dialysis on microinflammation of chronic renal failure(CRF)uremic patients and its relationship with cardiovascular disease.Methods A total of 120 CRF uremic patients treated in our hospital were divided into hemodialysis group(60 cases) and peritonealdialysis group(60 cases) according to the type of dialysis.After 6 months of treatment,the levels of C reactive protein(CRP),tumor necrosis factor(TNF)-α,interleukin(IL)-1β,IL-6 btween the two groups were compared.Patients in the two groups were divided into the group with and without chronic heart failure(CHF) according to the presence or absence of combined with CHF,the levels of TNF-α、IL-1β,IL-6 in each group were compared.Results There were no significant differences in the levels of CRP,TNF-α,IL-1β,IL-6 between the two groups before treatment(P>0.05).After treatment,the levels of TNF-α,IL-1β,IL-6 in both groups were significantly reduced than the same group before treatment(P<0.05),the levels of TNF-α,IL-1β,IL-6 in the peritoneal dialysis group were lower than those in the hemodialysis group(P<0.05).In patients with CHF,the levels of TNF-α,IL-1β,IL-6 in patients of the group with heart failure were significantly higher than those in the same group of the group without heart failure(P<0.05).Conclusion Both hemodialysis and peritoneal dialysis can reduce the level of TNF-α,IL-1β,IL-6 in CRF uremic patients,and peritoneal dialysis is better.Microinflammation is correlated with cardiovascular disease.

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